The article presents detailed guidelines for the nonlinear modelling of wood–CFRP beams with full cross-section using the Finite Element Method (FEM). Reviewing the literature has shown that behaviour of such composites is a current research topic, undertaken by many scientists. Complex numerical models made in the Simulia ABAQUS software are the basis for modelling recommendations. Properties of the materials consider the orthotropy and plasticity of wood and CFRP tapes, and the stiffness of adhesive layers with delamination. Results of laboratory experiments, got for a statistically significant number of specimens, confirm the model assumptions. This research paper provides a rich source of knowledge and experiences for scientists and engineers, who deal with mechanics of wood–CFRP composites. The uniqueness of the presentation lies in the detailed description of the complex numerical model. Specification comprises the steps necessary to do complete and successful calculations. The model is suitable for analysing the behaviour of wood–CFRP composites in different reinforcement configurations.