The paper presents a proposal for the assessment of the reliability of steel truss (both statically determinate and indeterminate) in the persistent and accidental design situation. In the analysis, a probabilistic approach was used. The global Hasofer-Lind reliability index was employed, computed in successive time steps for the whole structure, not for individual elements. The statically determinate truss was modelled as a serial system from the reliability standpoint. For the statically indeterminate truss, kinematically admissible failure mechanisms were determined by means of the examination of the singularity of the stiffness matrix of the structure, converting the truss into a geometrically variable system. For the problem thus formulated, a serial-parallel reliability model was constructed. Monitoring the reliability index in the successive minutes of the fire makes it possible to estimate the probability of the structure failure, and to decide whether the required safety level is maintained.