The running speed of high-speed trains in the tunnel is as high as 350 km, which is very sensitive to the construction disturbance of the new shield tunnel. Therefore, it is of positive significance to study the influence of shield tunneling on existing high-speed railway lines and tunnel structures and control standards. Combined with centrifuge test and three-dimensional numerical simulation, the dynamic response of shield tunnel undercrossing existing high-speed railway tunnel is studied, and the influence of settlement joint and steel pipe pile reinforcement on existing tunnel is analyzed. Studies have shown that the existence of existing tunnels will reduce the surface settlement caused by tunnel excavation, but this shielding effect will be reduced if the influence of construction joints is considered. Therefore, if the construction joint is not considered in the numerical calculation, the ground deformation will be underestimated and the mechanical performance of the existing tunnel structure will be overestimated. In addition, steel pipe piles can effectively control the settlement of existing tunnels.