Glass is a material commonly used in construction. The development of technology related to it, and the increase in knowledge concerning its mechanical and strength properties offer opportunities for glass to be applied as a structural material. The advancement in glass structures, methods for their design, as well as guidelines and standards in this fields are being developed in parallel. This article describes the main assumptions contained in the German TRxV guidelines, the series of German DIN 18008 standards, and the European EN 16612, and EN 16613 standard. Moreover, the following article presents the concept of structural glass design included in the draft pre-standard prCEN/TS 19100, which provides the basis for the formulation of the European standard Eurocode 10. According to this pre-standard, structural elements of glass will be verified in four limit states, depending on the Limit State Scenario (LSS). Apart from the classic limit states, i.e., the ultimate limit state (ULS), and the serviceability limit state (SLS), it is also assumed to introduce a fracture limit state (FLS), and postfracture limit state (PFLS). The article also addresses the issue of laminated glass working in structural elements. Depending on the coupling between the glass panes and the polymer or ionomer interlayers, laminated glass can be divided into complete coupled or uncoupled, and can work in intermediate situations. The methods for determining the effective thickness contained in European standards and guidelines are discussed in this article.